頭蓋骨転移で発症した転移性腎細胞癌の1例

Abstract

We report a case of a 77-year-old woman who presented with skull metastasis as an initial manifestation of renal cell carcinoma (RCC). She suffered from headache and dysethesia in the right parietal lesion and was transferred to our hospital. CT of the head demonstrated a bone tumor with destruction of the parietal bone. MRI showed enhanced bone tumor attached with dura mater. CT of the abdomen and chest revealed a right renal tumor and sixth costal bone metastasis. The skull tumor was suspected to be metastasis from renal cell carcinoma. Surgical resection for parietal bone tumor was performed and pathologic examination revealed clear cell carcinoma. After surgical resection for the skull tumor, nephrectomy was performed. After nephrectomy, local radiation therapy (40Gy) to the sixth costal bone was given. At the 6-month follow-up, she was found to be in a stable state with no progression of skull metastasis. RCC should be part of differential diagnoses of skull tumors.