Crohn病に合併した糸球体腎炎の1症例

Abstract

A 23-year-old male with Crohn's disease accompanied by glomerulonephritis as one of the extraintestinal manifestations is described. The patient was admitted to the hospital because of facial edema, oliguria and diarrhea. Laboratory data revealed proteinuria and microhematuria in urine analysis, and depressed serum complement level. Biopsy specimen obtained from the kidney showed diffuse endocapillary proliferative glomerulonephritis ; IgG, IgM and C3 were deposited on the involved glomeruli. The deposition of immune complexes might be related to the pathogenesis of the glomerular lesion in this case.