地域集団健診で得られた血圧値の性状とその関連要因に関する横断研究

Abstract

To clarify the characteristics of blood pressure and to investigate the association with its relevant factors we performed a cross-sectional study for people participating voluntarily in community-based mass examinations in three villages in Nara Prefecture in Summer, 1991. The subjects involved in this study were 1,654 (647 men and 1,007 women) aged from 40 to 69. Mean systolic blood pressure (SBP) and diastolic blood pressure (DBP) of the men were 126.2 (SD 17.2) mmHg and 76.1 (10.9) mmHg, respectively. Those of the women were 124.5 (18.2) mmHg and 73.4 (10.1) mmHg. The prevalence of persons judged to be hypertensive by WHO's criteria were 6.2% for the men and 4.1% for the women. These figures are much smaller than the corresponding figures in other epidemiologic studies in Japan. The differences may reflect selection bias of the subjects in this study. Both serum total cholesterol (TC) and high density lipoprotein cholesterol (HDL) levels associated with gender, age and body shape type (BST) index. The TC level among obese people was significantly higher than that of thin people. On the contrary, the HDL level showed significantly higher mean value among the thin people than the obese. Multiple regression analysis on SBP indicated that BST index, age, TC and gender had significant partial regression coefficients while village and HDL did not. The older, obese men with a higher TC level are likely to have higher SBP. Also the obese men with a higher TC level were found to be likely to have higher DBP. These results suggest that BST and TC should be independent risks for increase in SBP and DBP. Intervention in obesity can be a advisable way for both prevention and treatment of hypertension.