著明な高アルドステロン血症を呈した本態性高血圧症の1例

Abstract

A 55-year-old man was admitted because of hypertension. He exhibited no clinical manifestation but hypertension. And he became normotensive during hospitalization. Though plasma aldosterone concentration ranged through remarkably high levels (1600 to 6900 pg/ml), daily urinary aldosterone excretion, plasma renin activity, serum potassium and arterial blood pH remained within normal limits. General endocrine function was normal and responses to all diagnostic tests of the adrenal gland were proved to fit normal patterns. Ultrasonographic scan, CT scan and adrenal scintigraphic scan did not detect adrenal tumor or hyperplasia. These findings suggest that in this case aldosterone determined by radioimmunoassay would have no effect on hypertension, and have no biological activity.