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01 奈良県立医科大学 >
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0112 紀要 >
01121 Journal of Nara Medical Association >
Vol.50 No.4 >
このアイテムの引用には次の識別子を使用してください:
http://hdl.handle.net/10564/534
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タイトル: | 乳癌の化学療法後に骨髄異形成症候群を発症した高齢者末期腎不全の1例 |
その他のタイトル: | A CASE OF MYELODYSPLASTIC SYNDROME WITH END STAGE RENAL DISEASE ASSOCIATED WITH CHEMOTHERAPY FOR BREAST CANCER |
著者: | 濱野, 一將 山野, 繁 川野, 貴弘 椎木, 英夫 橋本, 俊雄 土肥, 和紘 中村, 忍 |
キーワード: | 5-FU mitomycin C therapy-related MDS |
発行日: | 1999年8月31日 |
出版者: | 奈良医学会 |
引用: | Journal of Nara Medical Association Vol.50 No.4 p.333-337 |
抄録: | A case of chemotherapy-induced myelodysplastic syndrome (MDS) in a 78
-year-old female with pancytopenia is reported. The patient had developed left breast
cancer in March 1972. After a mastectomy, she was treated with 5-fluorouracil (5-FU) and
mitomycin C without radiotherapy. Mild pancytopenia was detected in January 1998. In
April 1998, red cell count was 1,540,000/μl, white cell count was 2,400/μl, and platelet
count was 69,000/μl. A bone marrow examination in April 1998 showed normal cellularity
with 24% blasts. There were dysplastic changes in the erythroid and granulocyte series, and
Auer rods in the cytoplasm. The patient was diagnosed as having therapy-related MDS
(RAEB-T). MDS is one of the most serious late complications related to chemotherapy.
Although alkylating agents are potentially leukemogenic in patients with therapy related-
MDS, in this case MDS developed after treatment with 5-FU and mitomycin C. |
URI: | http://hdl.handle.net/10564/534 |
ISSN: | 13450069 |
出現コレクション: | Vol.50 No.4
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