エキシマレーザー照射による角膜の組織学的変化に関する実験的研究

Abstract

The present paper reports the investigation of corneal histopathological changes after excimer laser ablation in rabbits and fresh porcine eyes. In the ablated area, there are thickening of the epithelium, discontinuous basement membrane of the basal epithelial cells, and scarring of the superficial stroma. These changes are especially marked in severely ablated corneas, but they become less marked as time passes by. Linear electron-dense material is present in Descemet's membrane even in clinically weakly ablated eyes.