ハイリスク新生児の精神発達に関する予後調査研究 : 奈良県立医科大学附属病院新生児集中治療部で管理を受けた72例を対象として

Abstract

To clarify developmental outcone and its relationship to risk factors for high risk newborn infants, a longitudinal prospective study was done on 72 infants, Subjects aged from one through seven had been admitted to the Neonatal Intensive Care Unit (NICU) at Nara Medical University Hospital. The follow up evaluations were performed every half year for the infants aged under three, and every year for those over that age, and consisted of five examinations. They were assessments of risk factors, developmental quotient (DQ), early infantile behavioral problems, physical measurement and home envi- ronment estimated by Japanese Home Screning Questionnarie (JHSQ). The results were summarized as follows : 1. The DQ of the subjects at each age was within the normal range. On the subjects of four years and up, the DQ's were high in 'Self-help' and low in 'Language'. 2. The weight of the subjects at each age was lower than the median value of the Japanese. The head circumference was roughly equal to the median value. Height, weight and head circumference measurements significantly correlated with the DQ in the subjects aged three. 3, The significant risk factors for DQ were abnormalities of parents' characters, maternal stress during pregnancy, infantile heart disease, anemia and long-term endotra- cheal intubation. As the result of quanification method I, the effects of each risk factor on the DQ were put in order as follows : (1) infantile heart disease, (2) past abortions, (3) birth weight, (4) abnormalities of brain CT, and (5) family illness. 4. About early infantile behavioral problems, little babble and lost speech significantly affected the DQ in a negative way. 5. Home envimonment of subjects aged three correlated well with the DQ.