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GINMU >
01 奈良県立医科大学 >
011 医学部 >
0112 紀要 >
01121 Journal of Nara Medical Association >
Vol.46 No.3 >
このアイテムの引用には次の識別子を使用してください:
http://hdl.handle.net/10564/824
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| タイトル: | DENTATORUBRAL-PALLIDOLUYSIAN ATROPHY (DRPLA) AND MIDLATENCY AUDITORY EVOKED RESPONSES |
| 著者: | Kishimoto, Toshifumi
Higashiura, Naoto
Hiraoka, Yukie
Sakiyama, Shinobu
Kirita, Ikuhiro
Noriyama, Yoshinobu
Itoh, Naoto
Ueda, Atsushi
Oribe, Hiroaki
Ikawa, Genro |
| キーワード: | midlatency auditory evoked responses
DRPLA
molecular diagnosis
P1 abnormality |
| 発行日: | 1995年6月30日 |
| 出版者: | 奈良医学会 |
| 引用: | 奈良医学雑誌 Vol.46 No.3 p.251-258 |
| 抄録: | The human 'P1' middle latency evoked potential is postulated to be generat-
ed in the thalamus by a cholinergic component of the ascending reticular activating system.
To test the midbrain function of dentatorubral-pallidoluysian atrophy (DRPLA), recording
of middle latency response to click stimuli were carried out in a DRPLA family which was
detected with the aid of molecular diagnosis. Comparisons between the DRPLA members
and the normal members indicated normal Pa responses but P1 component is abnormal in
DRPLA. This P1 abnormality suggests that the midbrain cholinergic cells in DRPLA may
be dysfunctional. |
| URI: | http://hdl.handle.net/10564/824 |
| ISSN: | 04695550
13450069 |
| 出現コレクション: | Vol.46 No.3
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